In this special EAS edition of Z-APPS we have included three new
application notes that feature separations on the ZirChrom®-CARB
phase. This research explores how the unique selectivity and
stability of ZirChrom®-CARB can be employed to meet the toughest
ZirChrom will be exhibiting at the upcoming
AAPS National Biotechnology Conference in San Diego. To
learn more about this cutting edge research
visit us at our EAS booth #419 on May 1-2nd, 2017.
Rentention of 22 Solutes on ODS, ZirChrom®-PBD
and ZirChrom®-CARB -
Comparison of retention of these 22 solutes shows the orthogonal
selectivity of ZirChrom®-CARB
phase when compared to both ODS and ZirChrom®-PBD.
This unique selectivity allows separation of hard to resolve closely
related compounds and impurities.
- Full Application Note)
Fast Methods for Structually Similar Compounds
Method development in reversed-phase liquid chromatography (RPLC) has
traditionally been difficult for molecules which are geometric isomers
or structurally very similar. In bonded-phase silicas, the partition
mechanism responsible for retention in RPLC often does not offer
adequate chemical selectivity for such compounds. ZirChrom®-CARB provides
retention in RPLC through an adsorption mechanism which often times
increases the chromatographic selectivity for these types of compounds
and dramatically increases the chances of resolving pairs of these
analytes. In addition to this enhanced chromatographic selectivity,
offers increased chemical and stability of the stationary phase - pH
1-14 and temperatures up to 200°C.
Full Application Note)
Fast Separation of Acrylamide Monomer from Acrylic Acid on ZirChrom®-CARB
Small polar molecules such as acrylamide and acrylic acid can be
difficult if not impossible to separate on conventional reversed-phase
bonded silica type phases using HPLC. Acrylamide historically has been
analyzed using sample derivitization coupled with gas chromatography.
The distinctive selectivity and increased retentiveness of the
phase, compared to bonded silica or polymeric phases, enables the
baseline resolution of these small polar molecules.
- Full Application Note)
ZirChrom Separations will be exhibiting at AAPS
NBC 2017 on
May 1st through May 2nd. ZirChrom technical experts will
be staffing the ZirChrom booth, booth #419, and would be happy to
assist with your most difficult separations.
place an order for our
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