ZAPPS Volume 17:  

ZirChrom®-PBD, a Superior Choice for the Validated Analysis of Basic Pharmaceuticals.

In this special EAS edition of Z-APPS we have included three new application notes that feature separations on the ZirChrom®-PBD phase.  This research explores how the unique selectivity and stability of ZirChrom®-PBD can be employed to meet the toughest separation validation challenges for basic pharmaceuticals.

ZirChrom will be exhibiting at the upcoming Eastern Analytical Symposium at the Crowne Plaza Princeton in Plainsboro, NJ.   To learn more about this cutting edge research visit us at our EAS booth #B21 in the Einstein Room on November 13-15th, 2017.

Fast Separation of Triptans in Rat Plasma on ZirChrom®-PBD - The following reviews a published comparison by Ahmed and Atia, at Taibah University (Saudi Arabia) and Assiut University (Egypt) of the ZirChrom®-PBD column to the Hypersil BDS C18 column for the analysis of triptans in rat plasma.  This pioneering work concluded that the ZirChrom®-PBD had a superior selectivity for these analytes; allowing for an isocratic method with comparatively enhanced selectivity, peak shape and efficiency with an analysis time of less than six minutes.  (PDF - Full Application Note)

Stability of ZirChrom®-PBD for the Fast Separation of Triptans - The following reviews a published novel analysis by Ahmed and Atia, at Taibah University (Saudi Arabia) and Assiut University (Egypt) of four triptans in rat plasma using the ZirChrom®-PBD column.  This pioneering work concluded that the ZirChrom®-PBD phase had superior selectivity for these analytes.  In this application note we present the author's findings regarding the stability of this method on the ZirChrom®-PBD phase.   (PDF - Full Application Note)

Analysis of Azithromycin using ZirChrom®-PBD - The ZirChrom®-PBD column has been designated by the USP as L49 and can be used for the analysis of azithromycin.  The pH required for the stability of the azithromycin analytes requires a high pH compatible column such as the ZirChrom®-PBD phase. This application note presents the pH 11.0 analysis of azithromycin on ZirChrom®-PBD.   (PDF - Full Application Note)

Join Us! - ZirChrom Separations will be exhibiting at EAS 2017 on November 13th through November 15th.  ZirChrom technical experts will be staffing the ZirChrom booth, booth #B21 in the Einstein Room, and would be happy to assist with your most difficult separations.

To place an order for our products, or for more information, please contact us at 1-866-STABLE-1 or support@zirchrom.com .

 

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