NOW AVAILABLE - Short ZirChrom Columns for UFHTLC

ZirChrom now offers short (2 cm) all-stainless steel pre-columns for ultra-fast high temperature reversed-phase liquid chromatography. These columns are only sold in sets of two. Mix and match ZirChrom chemistries if you like! Contact ZirChrom technical support at 1-866-STABLE-1 for more details, or feel free to contact us online. Part #ZR03-SPEC (for ZirChrom-PBD).

NOW AVAILABLE - ProTain In-Line Protein Removal System

The incorporation of ZirChrom's new ProTain in-line protein removal system upstream of any type of analytical column offers a selective, cost effective and simple method of reducing matrix interferences for the HPLC analysis of small molecules in bio-samples. Click here for more information about the ProTain In-Line Protein Removal System.

ZirChrom Separations Inc. Recieves New Patent

ZirChrom Separations announces the issue of a patent (US 8,137,548 B2) for its covalently attached Lewis acid deactivation chemistry.  This technology was first introduced with the ZirChrom^®-MS phase and culminated in the development of the ZirChrom^®-Chiral line of stationary phases.  PRESS RELEASE (Adobe Acrobat Reader required)

ZirChrom Separations Inc. Launches ChromU On-Demand Webinar Series

ZirChrom Separations Inc. announces the launch of ChromU, an on-demand webinar series.  This free service will provide training on the chemistry and use of ZirChrom's zirconia-based HPLC phases.  ChromU webinars are, on average, less than 10 minutes in length and include links to helpful supplemental application notes and newsletters.  PRESS RELEASE (Adobe Acrobat Reader required)

ZirChrom Separations Inc. Unveils New Sub-2mm Particles

The superior physical and chemical stability of ZirChrom phases allow for the full realizatio nof the potential of sub-2 micron particles.  This increased stability allows the average HPLC user to take advantage of the increased efficiency provided by the smaller particles without the use of specialized UHPLC instrumentation.    PRESS RELEASE (Adobe Acrobat Reader required)

ZirChrom Separations Inc. Unveils New Phosphorylated Peptide Enrichment Protocol

ZirChrom Separations Inc. introduced six new application notes employing both titanium dioxide and zirconium dioxide for phosphopeptide enrichment at the Eastern Analytical Symposium 2006 Trade Show in Somerset, NJ. Titanium dioxide and zirconium dioxide media are fast becoming the new standards for the enrichment of phosphorylated peptides used in mass spectrometry (MS) analysis.  Complex peptide mixtures enriched with revolutionary titania-based and zirconia-based solid phase extraction (SPE) media display exceptional signal to noise ratios. PRESS RELEASE (Adobe Acrobat Reader required)

ZirChrom Separations Introduces New ZirChrom-SELECT HPLC Columns

A next generation carbon-based HPLC column, ZirChrom -SELECT, will be introduced by ZirChrom Separations, Inc. at the Pittcon 2005 Trade Show in Orlando, FL. The new surface deactivated ZirChrom -SELECT column provides improved peak shape and ease of use compared to other commercially available carbon-based HPLC columns. ZirChrom will introduce its new product at the Orange County Convention Center, Booth #2801 from February 28 through March 3, 2005. PRESS RELEASE (Adobe Acrobat Reader required)

ZirChrom Separations Inc. and Sachtleben Chemie GmbH Launch New Reversed-Phase Analytical and Preparative Chromatography Columns

ZirChrom Separations, Inc. and Sachtleben Chemie GmbH announced their cooperation in the packing, marketing and sales of titania-based HPLC columns. These next generation columns are offered in both analytical and preparative formats, containing a wide selection of particle (3, 5, 10, 20, 50 and 100 micron) and pore (60, 100, 300, and 1000 angstrom) sizes. Sachtleben brings a long-standing tradition of excellence to the chromatography market as well as the capability to produce large quantities of particles very reproducibly. Sachtopore-RP, the newest titania-based reversed-phase, was introduced at the PREP 2004 (Preparative / Process Chromatography) trade show in Baltimore, MD. A normal phase titania packing is also available. These new titania-based columns offer the chromatographer a very rugged alternative to silica for both analytical and preparative-scale separations.  PRESS RELEASE (Adobe Acrobat Reader required)

ZirChrom Separations Introduces ZirChrom-MS for LC/MS Applications

A next generation HPLC column for LC/MS applications, ZirChrom-MS, was introduced by ZirChrom Separations, Inc. at the EAS (Eastern Analytical Symposium) 2003 Trade Show in Somerset, NJ. The new surface deactivated ZirChrom -MS columns offer enhanced retention, unique selectivity, and improved peak shape for basic pharmaceutical compounds compared to other columns currently on the market. PRESS RELEASE (Adobe Acrobat Reader required)

ZirChrom Separations Introduces ZirChrom-EZ - An Easy-To-Use Chromatographic Media

A next generation, easy-to-use chromatographic media for analytical and preparative chemical separations, ZirChrom-EZ, was introduced by ZirChrom at PITTCON 2003 in Orlando, FL. ZirChrom -EZ provides the traditional unique selectivity of zirconia while facilitating the buffer selection process in the pH range of 1-10. This new ease-of-use capability, along with its orthogonal selectivity for pharmaceutical compounds, makes ZirChrom -EZ well suited for LC/MS applications.

ZirChrom Separations Garners 2002 Tibbett's Award

Clayton V. McNeff, PhD, Vice President, ZirChrom Separations, Inc., is a recipient of the 2002 Tibbett's Award from the Federal Small Business Innovation Research (SBIR) program. The award is presented each year to small firms, organizations and individuals judged to exemplify the very best in SBIR achievement. PRESS RELEASE (Adobe Acrobat Reader required)

ZirChrom Separations Garners Award for Research Advancements in Chromatography

ZirChrom Separations will receive an award recognizing its entrepreneurial spirit and innovative excellence from Minnesota Project Innovation. The award will be presented on April 26, 2002, in Minneapolis, MN. ZirChrom will be honored with the Federal Agency Award, presented to companies that have researched, developed and successfully marketed key technologies with funding from federal grants. PRESS RELEASE (Adobe Acrobat Reader required)

ZirChrom "A-Page" Article Published in Analytical Chemistry

Analytical Chemistry (November 1, 2001; p. 598A-607A) published an article entitled "Zirconia Stationary Phases for Extreme Separations". This article summarizes some of the recent advances that have been made in zirconia-based HPLC stationary phases. ARTICLE ACCESS - ACS MEMBERSHIP REQUIRED

ZirChrom Separations Awarded Phase IIB SBIR Grant to Study Ultra-fast LC

ZirChrom Separations was awarded a $350,000 Phase IIB SBIR grant from the National Science Foundation to study the manufacture of a very broad family of chemically and thermally stable monomer-type composite materials for ultra-fast liquid chromatography. This work will be conducted in collaboration with ZirChrom's new strategic partner Cabot Corporation (Billerica, MA). The project will seek to combine the carbon chemical vapor deposition technology developed by ZirChrom with Cabot's patented technology for covalently modifying the surface of carbon particles.

ZirChrom Separations Introduces DiamondBond - A New Class of HPLC Columns

A new class of HPLC columns for analytical and preparative chemical separations, DiamondBond, was introduced by ZirChrom at PITTCON 2001 in New Orleans, LA. The new DiamondBond columns offer a broader range of selectivity, higher efficiency and unparalleled durability compared to other columns currently on the market. PRESS RELEASE (Adobe Acrobat Reader required)

ZirChrom Study Published in May 2000 Edition of LC*GC Magazine

LC*GC Magazine published an article entitled "Analytical Advantages of Highly Stable Stationary Phases for Reversed-Phase Liquid Chromatography". This article describes a study conducted by technical experts at ZirChrom Separations. In the study, the authors used a wide variety of test solutes to compare the efficiency, selectivity, and hydrophobic retention mechanisms of five commercially available reportedly "stable" HPLC columns based on silica (ODS silica), alumina (PBD coated alumina), zirconia (Zirchrom-PBD and Zirchrom-CARB), and polystyrene cross linked with divinylbenzene (PS-DVB) as the support. ARTICLE (Adobe Acrobat Reader required)

ZirChrom Separations Awarded Phase II SBIR Grant to Study Preparative-Scale Zirconia

ZirChrom Separations was awarded a $750,000 Phase II SBIR grant from the National Institute of Health to study the manufacture of large zirconia particles for the preparative-scale purification of bio-molecules. PRESS RELEASE (Adobe Acrobat Reader required)

ZirChrom Columns Earn Positive Customer Feedback

Novartis Crop Protection reports a significant improvement in the separation and purification of basic compounds using ZirChrom-PBD. Another major pharmaceutical company touts the merits of ZirChrom-PBD. (Adobe Acrobat Reader required)

ZirChrom Separations Awarded Phase II SBIR Grant to Study Nonporous Zirconia

ZirChrom Separations was awarded a $400,000 Phase II SBIR grant from the National Science Foundation to study the manufacture of nonporous zirconia for ultrafast liquid chromatography. PRESS RELEASE (Adobe Acrobat Reader required)

Press Articles Pertaining to ZirChrom Products

LC*GC lauds ZirChrom columns as the most novel for 1998. Inventing Tomorrow does a feature article on the evolution of the ZirChrom technology. Pharmaceutical Formulation & Quality interviews one of ZirChrom's founders. (Adobe Acrobat Reader required)